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08. Feb. '12
Studies
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• Antioxidant / Anticlastogenic / Radioprotective: Antioxidant, anticlastogenic and radioprotective effect of Coleus aromaticus on Chinese hamster fibroblast cells (V79) exposed to gamma radiation: The hydroalcoholic extract of CA showed dose-dependent radical scavenging against free radicals, rendered radioprotection against radiation induced DNA damage. Study results establsihed antioxidant, anticlastogenic and radioprotective activities and suggests a potential for chemoprevention.
• Antioxidant: Study of freeze-dried aqueous extract of Ca clearly established the antioxidant potency of freeze-dried extract of C aromaticus.
• Mast cell stabilization property: Study showed stabilization of mast cells in rat mesenteric tissue and suggests further studies into mast cells with its role in Type 1 hypersensitivity-mediated diseases like asthma and rhinitis.
• Antimicrobial: (1) Antimicrobial Activity Of Coleus aromaticus (Benth) Against Microbes Of Reproductive Tract Infections Among Women : Results suggests the herb could be an ideal choice for treating reproductive tract infections. (2) Study showed the antimicrobial effect of Coleus ambonicu, Lour folium infuum toward C albican and Strep mutans.
• Anticlastogenicity: Study of ethanolic extract of C aromaticus showed a protective effect against cyclophophamide and mitomycin-C induced cytogenetic damage.
• Anti-Inflammatory: In a carrageenan-induced rat paw edema model, the aqueous extract of Coleus aromaticus exhibited potent anti-inflammatory activity, attributed to the inhibition of mediators released from the 2nd phase of inflammation.
• Antibacterial: Study showed both ethanol and hot water leaf extracts of Coleus aromaticus to possess potent antibacterial activity, the ethanol extract showing greater activity. Results provide scientific support for the centuries-old use of the plant as a medicinal herb.
• Forskolin / Antioxidant / Anti-Asthma / Pulmo-protective: Study isolated forskolin, a diterpenoid, from a methanolic extract of C aromaticus. C aromaticus has been used to treat asthma. Forskolin has been thought to be responsible for its pharmaceutical activity through resotration of antioxidant enzyme activity with its ability to scavenge free radicals. The results validate the use of forskolin as an anti-asthmatic agent.



. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
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